Dorzolamidetimolol n47 AZARGA Suspension vs dorzolamidetimolol fixed

Dorzolamidetimolol n47 azarga suspension vs

This preview shows page 15 - 22 out of 30 pages.

Dorzolamide/timolol (n=47)
Image of page 15
AZARGA® Suspension vs. dorzolamide/timolol fixed combination Comfort Study Vold SD, Evans RM, Stewart RH, et al. A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension. J Ocul Pharmacol Ther . 2008;24:601-605. Dorzolamide/t imolol (n=7)
Image of page 16
AZARGA® Suspension vs. dorzolamide/timolol fixed combination Comfort Study Vold SD, Evans RM, Stewart RH, et al. A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension. J Ocul Pharmacol Ther . 2008;24:601-605. Dorzolamide/timolol
Image of page 17
AZARGA® Suspension vs. dorzolamide/timolol fixed combination Comfort Study Summary AZARGA ® Suspension is significantly more comfortable than dorzolamide/ timolol fixed combination*. A significantly higher percentage of patients (49%) using AZARGA ® Suspension experienced no ocular burning or stinging compared to patients on dorzolamide/ timolol fixed combination* (15%) (p=0.0004). * Trademark is the property of its owner. Vold SD, Evans RM, Stewart RH, et al. A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension. J Ocul Pharmacol Ther . 2008;24:601-605.
Image of page 18
OBJECTIVE: To determine patient preference of brinzolamide 1%/timolol 0.5% compared to dorzolamide 2%/timolol 0.5% DESIGN: Prospective, double-masked, randomized, multi- center crossover study TREATMENT ARMS : 1- AZARGA® Suspension, then dorzolamide/timolol fixed combination * (n=63 patients) 2- dorzolamide/timolol fixed combination then AZARGA® Suspension (n=66 patients) * Trademark is the property of its owner. Mundorf TK, Rauchman SH, Williams RD, et al. A patient preference comparison of Azarga (brinzolamide/timolol fixed combination) vs Cosopt (dorzolamide/timolol fixed combination) in patients with open-angle glaucoma or ocular hypertension. Clin Ophthalmol . 2008;2:623-628. AZARGA® Suspension vs. dorzolamide/timolol fixed combination Preference Study
Image of page 19
AZARGA® Suspension vs. dorzolamide/timolol fixed combination Preference Study VISITS : Screening, Day 1, Day 2 Discomfort Score collected on Day 1, Day 2 DISCOMFORT SCALE 0=No discomfort to 9=Substantial discomfort Preference Question collected on Day 2 POSSIBLE RESPONSES: Prefer 1st medication, No preference, Prefer 2nd medication
Image of page 20
AZARGA® Suspension vs. dorzolamide/timolol fixed combination Preference Study Mundorf TK, Rauchman SH, Williams RD, et al. A patient preference comparison of Azarga (brinzolamide/timolol fixed combination) vs (dorzolamide/timolol fixed combination) in patients with open-angle glaucoma or ocular hypertension. Clin Ophthalmol . 2008;2:623-628.
Image of page 21
Image of page 22

You've reached the end of your free preview.

Want to read all 30 pages?

  • Fall '17

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture

Stuck? We have tutors online 24/7 who can help you get unstuck.
A+ icon
Ask Expert Tutors You can ask You can ask You can ask (will expire )
Answers in as fast as 15 minutes