Pernicious anemia is most common among people of Northern European descent, though it’s also found in other populations. Those at increased risk of developing the condition include
people who lack intrinsic factor, who can’t properly absorb vitamin B12, or who don’t get enough vitamin B12 in their diets. People who lack intrinsic factor, Intrinsic factor attach to vitamin B12 and take it to the intestines, where it is absorbed. An individual with the underline or chronic disease are at risk to developed Pernicious anemia, such as Addison’s disease, type 1 diabetes, Graves’ disease, and vitiligo can cause this type of autoimmune response. Rarely, children are born with a condition called congenital pernicious anemia. This disorder prevents their bodies from making intrinsic factor. Pernicious anemia is most common among people of Northern European descent, though it’s also found in other populations. Those at increased risk of developing the condition include people who lack intrinsic factor, who can’t properly absorb vitamin B12, or who don’t get enough vitamin B12 in their diets.SummaryPernicious anemia is diagnosed based on your medical and family histories, a physical exam, andthe results from tests. As clinician is it always best to assess the patient for clinical presentation, signs and symptoms, diet, skin condition, and tongue, listen to your heart, and check for signs of nerve damage. This will help the clinician learn more about the severity the disorder (anemia) and how the disorder is affecting the body. Diet and other illnesses or conditions you have that could be related (such as intestinal disorders that affect your ability to absorb iron from food). History of woman menstrual and pregnancy history. Assess skin and nails and listen to your heart and lungs.References:Hammer, G. G., & McPhee, S. (2014). Pathophysiology of disease: An introduction to clinical medicine. (7th ed.) New York, NY: McGraw-Hill Education.
American Sickle Cell Anemia Association. (2010). Retrieved from Smith DL. Anemia in the elderly. Am Fam Physician. 2000;62:1565 -1572. MedlineWorld Health Organization. A guide for program managers. Geneva (Switzerland): World Health Organization; 2001. Iron deficiency anemia assessment, prevention, and control.
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- keisha lovence