These deficiencies lead to defective erythrocytes that die prematurely which

These deficiencies lead to defective erythrocytes

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These deficiencies lead to defective erythrocytes that die prematurely, which decreases their numbers in the circulation, causing anemia. It is not due to a lack of differentiation.These deficiencies lead to defective erythrocytes that die prematurely, which decreases their numbers in the circulation, causing anemia. It is not due to malformed hemoglobin.These deficiencies lead to defective erythrocytes that die prematurely, which decreases their numbers in the circulation, causing anemia. It is not due to decreased oxygen carrying capacity.REF:p. 50611.A 20-year-old female undergoes lab testing for anemia. Results show high iron, bilirubin, and transferrin and low hemoglobin and hematocrit. Which of the following is the most likely diagnosis to be documented on the chart?a.Pernicious anemiab.Folate deficiency anemiac.Iron deficiency anemiad.Sideroblastic anemiaANS:DIndividuals with sideroblastic anemia may show signs of iron overload (hemosiderosis), including mild to moderate enlargement of the liver (hepatomegaly) and spleen (splenomegaly).High levels of iron indicate sideroblastic anemia, not pernicious anemia.High levels of iron indicate sideroblastic anemia, not folate deficiency.High levels of iron indicate sideroblastic anemia, not iron deficiency anemia.
REF:p. 50512.A 35-year-old female is diagnosed with vitamin B12deficiency anemia (pernicious anemia). Howshould the nurse respond when the patient asks what causes pernicious anemia? A decrease in ______ is the most likely cause.a.Ferritinb.Gastric enzymesc.Intrinsic factord.ErythropoietinANS:CThe underlying alteration in pernicious anemia (PA) is the absence of intrinsic factor (IF), an enzyme required for gastric absorption of dietary vitamin B12, a vitamin essential for nuclear maturation and DNA synthesis in red blood cells.PA is not due to a decrease in ferritin, but a lack of the intrinsic factor.PA is not due to a decrease in gastric enzymes, but a lack of the intrinsic factor.PA is not due to a decrease in erythropoietin, but a lack of intrinsic factor.REF:p. 50113.Which of the following individuals should the nurse assess first for a vitamin B12deficiency anemia?a.3-year-old female who is a fussy eaterb.26-year-old female in the second trimester of her first pregnancyc.47-year-old male who had a gastrectomy procedure (removal of the stomach)d.64-year-old male with a history of duodenal ulcers and gastrointestinal bleeding
ANS:CWith removal of the stomach, the intrinsic factor is also removed, leading to an inability to absorb B12; thus, the person with removal of the stomach is at greatest risk.With removal of the stomach, the intrinsic factor is also removed, leading to an inability to absorb B12; thus, the person with removal of the stomach is at greatest risk, not the person who is a fussy eater.

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