In immunology the response that marks the adaptive

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in immunology, the response that marks the adaptive immune system’s first encounter with a particular antigen Regulatory T Cell: type of lymphocyte that helps control the immune response Secondary Lymph Organ: peripheral lymphoid organs where mature lymphocytes function in immune responses o Include adenoids, tonsils, spleen, appendix, and lymph nodes, among others Secondary Response: enhanced immune response that occurs upon second or subsequent exposure to specific antigen, caused by the rapid activation of long-lived memory cells o Anamnestic Response Skin-Associated Lymphoid Tissue (SALT): secondary lymphoid tissue consisting of collections of lymphoid cells under the skin T Cell Receptor: molecule on a T cell that enables the T cell to recognize a specific antigen T Lymphocytes: lymphocytes that mature in the thymus, responsible for cellular immune responses and function as helper cells in the antibody response T-Dependent Antigen: antigens that evoke an antibody response only with the participation of Helper T Cells T-Independent Antigen: antigens that can activate B cells without the assistance of a Helper T Cell Variable Region: the portion of an antibody molecule that contains the antigen-binding sites o Tremendous variation exists between the amino acid sequences of variable regions in different antibody molecules
Chapter 17 Allergen: antigen that causes an allergy Allergy: hypersensitivity, especially of the IgE-mediated type Allografts: organ or tissue transplanted between genetically nonidentical members of the same species Antibody Deficiency: common primary immunodeficiency in which little or no IgA is produced have repeated bacterial infections of respiratory, gastrointestinal, ad genitourinary tracts o May also have Agammaglobulinemia; disease in which few or no antibodies are produced Arthus Reaction: hypersensitivity reaction caused by immune complexes and neutrophils Asthma: immediate respiratory allergy resulting from the release of mediators form mast cells in the lower airways Autoimmune Disease: disease produced as a result of an immune reaction against one’s own tissues Degranulation: release of mediators from a cell’s granules, such as histamine is released from mast cells Delayed-Type Hypersensitivity: hypersensitivity caused by cytokines released from sensitized T lymphocytes Disseminated Intravascular Coagulation: devastating condition in which clots form in small blood vessels, leading to failure of vital organs Grave’s Disease: organ specific autoimmune disease affecting the thyroid gland o Metabolic rate increases, resulting in weight loss, fatigue, irritability, heat intolerance, rapid heartbeat, and bulging eyes Hay Fever: allergic rhinitis sneezing, runny nose, teary eyes resulting from exposure of a sensitized person to inhaled antigen o An IgE-mediated allergic reaction Hemolytic Disease of the Newborn:

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