Inflammatory response increased blood supply

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Inflammatory Response • Increased blood supply • Accumulation of white blood cells at site of infection/injury • Chemicals/proteins that promote inflammation —histamines, cytokines, free radicals, prostaglandins • Examples of inflammatory response: pimple, gastritis, laryngitis, mucus production
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26 Steps in Inflammatory Response Platelets Histamine Phagocytic cell Bacteria Skin Wound 4 3 2 1 1. Damaged tissues release histamine which increases blood flow 2. Histamine causes capillaries to leak releasing phagocytic cells and clotting factors 3. Phagocytic cells engulf bacteria, dead cells and debris 4. Platelets seal the wound
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27 Inflammation Nonspecific reaction to noxious stimuli 5 classic signs of inflammation: • Erythema (redness) • Edema (swelling) • Pain • Heat (fever) • Altered function
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28 Inflammation Movie http://www.youtube.com/watch?v=CmbWE3jLUgM&feature=related http://www.youtube.com/watch?v=suCKm97yvyk&feature=related
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29 Schematic illustration of blood vascular and lymphatic system
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30 Blood — Lymph Capillary Exchange
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31 Lymphatics and Organs of the Immune System Fluid = lymph Vessels = lymphatics
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