Regulation of the cac when glucose blood level

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Regulation of the CAC
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Fig. 16-15 • When glucose blood level increases, insulin is released to the blood. • Another mechanism of insulin action is activation of glycogen synthesis. •The hormone binding to the insulin receptor leads to activation of pyruvate dehydrogenase phosphatase . •The enzyme dephosphorylation promotes the synthesis of acetyl- CoA. Regulation of the CAC
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Regulation of the CAC • Ca 2+ is the cellular second- messenger that stimulates muscle contraction. •Simultaneously, Ca 2+ inhibits pyruvate dehydrogenase kinase but activates pyruvate dehydrogenase phosphatase, isocitrate dehydrogenase, and α - ketoglutarate dehydrogenase.
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