Can involve severe sudden onset life threatening

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Can Involve Severe, Sudden Onset Life-threatening Treatment-limiting Side-Reactions Limited by Tumor Heterogeneity, Selection for Unresponsive Variants, and Emergence of Immune-Escape ImmunOpt
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Host-Response Modification in Cancer Management Potentially Less Intrusive than Other More-Aggressive Modalities Treating Host Supporting Cells to Reduce their ability to promote tumor growth (e.g. anti-angiogenesis) Host stromal cell interactions supporting tumor growth: “Respect Thy Neighbor!” Science, Feb. 6, 2004 (BIO 501 Web-Site: Password-protected Link) Host Mod
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Gene Therapy for Cancer Potentially Highly Tumor-Specific Accessibility of Cell Targets Is a Major Obstacle for General Application May Have Great Value in Combined Modality Approaches Potentially Dangerous Side-Reactions from Viral Vector Delivery Agents GeneTher
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Combined Modality Therapies for Cancer Surgery and Radiation Adjuvant Chemotherapy: Surgery and Chemotherapy Radio-sensitizers: Chemotherapy and Radiation Chemotherapy and Host-Response Modification Induction of Differentiation by Chemotherapeutic Agents Induction of Apoptosis by Chemotherapeutic Agents Immunotherapy and Gene Therapy Genetically Engineered T-Cells Chemotherapy with Ultra-sonic Disruption? Combined
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Figure 16.23 The Biology of Cancer (© Garland Science 2007) Emergence of Drug Resistance
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Table 16.2 The Biology of Cancer (© Garland Science 2007)
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Only three Presentations (and one half-term exam) to go! I’m Still here! 1. Yes 2. No
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BioAgents
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ChemoDrugs
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TissueFactors
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  • Spring '11
  • ThomasFondy
  • Oncology, Chemotherapy, External physical intervention

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