Lecture 13 – Muscle Physiology I

The sr has lateral sacs that lie up against and

Info icon This preview shows pages 3–5. Sign up to view the full content.

View Full Document Right Arrow Icon
The SR has lateral sacs that lie up against and communicate with the T-tubule There are proteins that do this  communication Surrounding each sucle cell is a specific arrangement of t tubules and SR Functional Contractile Unit  In myofibril In the sarcomere, gets sorter when muscles contract M-line myosin molecules attach there Zones Used now as references Sarcomeres are the function units Made up of a bunch of bands A band – mostly thinck filaments,s protiions of thin filaments that overlap on both ends  of thick filaments H –zone – lighter area in the middle of the A band where thin filaments do not reach M – line – extends vertically down the middle of A band within the center of the H zone Z-line is connected to myosin molecule by a giant protein Avt as a spring and allow muscle to have elastic recoil When it shortens it puts tension on the molecule The contraction is over and the relazxation of this protein allows it to come back via  recoil Nebulin helps hold the actin g-actin and f-actin Thick filaments are mostly myosin
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Titin Ginaty elastic proteins Largest protein in the body Extends in both direction for M line along the length of the thick filament to Z lines at  opposite ends of the sarcomere Roles of Titin Along with M-line protieins helps stabilize position of thick filaments in relation to thin  filaments Greatly augments the muscle’s elasticity by acting as a spring Regulatory st of proteins – troponin and tropomyosin, and nebulin (aligning proteins)
Image of page 4
Image of page 5
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern