Eat more arginine arginine citruilline supplements

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Eat more arginine -Arginine + Citruilline supplements toted as better than arginine alone. Promoting NO Synthesis You cannot put a gas in a pill! This is arginine!
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Promoting NO signaling 1) Hyperactivation of NMDA receptors 2) Inhibition of cGMP breakdown Viagra, Cialis, Levitra: cGMP- specific phosphodiesterase type 5 inhibitor -relaxation of vasculature, increased blood flow….but it’s not via a direct effect on NO per se but prolongs NO signaling when activated PDE
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Inhibiting NO Signaling - CAPON (carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase) is a newly discovered protein that binds to NOS and prevents its ability to associate with PSD- 95 no close association with NMDA receptor no activation by CaMK because it’s not anchored -CAPON is over-expressed in the PFC of schizophrenia patients and the gene is localized to a region of chromosome 1 highly associated with schizophrenia in linkage studies.
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