3 the enzyme topo relieves any tension from the

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3. The enzyme __________topo___________ relieves any tension from the unwinding of the double helix. 4. The enzyme _____________helicase__________ breaks the hydrogen bonds holding the two complementary parent strands together, resulting in an unzipped helix that terminates at the _________replication fork______________. 5. _________________SSBP___________ anneal to the newly exposed template strands, preventing them from reannealing. 6. The enzyme _______primase_______ lays down RNA primers that will be used by _____________DNA POL 3__________ as a starting point to build the new complementary strands. 7. _______________ DNA POL 3________ adds the appropriate deoxyribonucleoside triphosphates to the 3! end of the new strand using the template strand as a guide. The energy in the phosphate bonds is used to drive the process. 8. The _____________lead____ strand is built continuously toward the replication fork. The ____________lag______ strand, composed of short segments of DNA known as __________________________oka_____, is built discontinuously away from the replication fork. 9. _____________dna pol 1__________ excises the RNA primers and replaces them with the appropriate deoxyribonucleotides. _________dna ligase________________ joins the gaps in the Okazaki fragments by the creation of a ______phospho____________ bond. 10. _________pol 1______________ and _______pol 3________________ proofread by excising incorrectly paired nucleotides at the end of the complementary strand and adding the correct nucleotides.

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