Miah will be monitored for signs of fever and a blood culture will be sent to the lab for testing. Patient will be started on azithromycin 10mg/kg for 48 hours. Miah will have a biopsyand culture of the bone to rule out osteomyelitis with swollen hands and foot. Miah will also be started on Hydroxyurea 20 mg/kg/day on a fixed dosage. Studies have suggested that hydroxyurea significantly reduces pain crisis in sickle cell children and has minimal side effects leading to lower mortality rates (Gardner, 2018).ReferencesBurns, C., Dunn, A., Brady, M., Starr, N., & Blosser, C. (2016). Pediatrics primary care: Ahandbook for nurse practitioners, (6thed.) Philadelphia: Saunders.Gardner, R.V. (2018). Sickle cell disease: Advances in treatment. Ochsner Journal, 18(4), 377-389.Matte, A., Zorzi, F., Mazzi, F., Federti, E., Olivieri, O., & Franceschi, L. (2019). Newtherapeutic options for the treatment of sickle cell disease. Mediterranean Journal of
Hematology & Infectious Disease, 11(1), 1-12.Motwani, G., Mehta, R., Aroojis, A., & Vaidya, S. (2017). Current trends of microorganismsand their sensitivity pattern in pediatric septic arthritis: A prospective study fromtertiary care level hospital. Journal of Clinical Orthopaedics and Trauma, 8, 89-92.Pirenne, F., Bartolucci, P., & Habibi, A. (2017). Management of delayed hemolytic transfusionreaction in sickle cell disease: Prevention, diagnosis, treatment. Transfusion CliniqueetBiologique, 24(3), 227-231)Spiegel, L., Kristensen, K.D., & Herlin, T. (2015). Juvenile idiopathic arthritis characteristics:Etiology and pathophysiology. Seminars in Orthopaedics, 21(2), 77.Ware, R.E, de Montalembert, M., Tshilolo, L., & Abboud, M.R. (2017). Seminar: Sickle celldisease. The Lancet.
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- Summer '17
- Sickle-cell disease, MIAH, NSG6435 Week 5 Discussion