Antiemetics decreased incidence and severity of nausea and vomiting following

Antiemetics decreased incidence and severity of

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Antiemetics; decreased incidence and severity of nausea and vomiting following chemotherapy Blocks the effects of serotonin at 5-HT3 receptor sites (selective Prevention of nausea and vomiting associated with highly or moderately emetogenic Serotonin syndrome, headache, dizziness, drowsiness, fatigue, weakness, torsade Monitor ECG in patients wit h hypokalemia, hypomagnesemia, HF, bradyarrhythmias, or patients taking concomitant medications that prolong the QT interval;
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or surgery antagonist) located in vagal nerve terminals and the chemoreceptor trigger zone in the CNS chemotherapy; de pointes, QT interval prolongation, constipation, diarrhea, abdominal pain, dry mouth, increased liver enzymes, extrapyramidal reactions, stevens- johnson syndrome, toxic epidermal necrolysis monitor for signs and symptoms of serotonin syndrome, assess for rash Metoclopramide/ Reglan Antiemetics Blocks dopamine receptors in chemoreceptor trigger zone of the CNS; stimulates motility of the upper GI tract and accelerates gastric emptying Used in conjunction with an opioid to prevent or treat emesis Drowsiness, extrapyramidal reactions, restlessness, neuroleptic malignant syndrome, anxiety, depression, irritability, tardive dyskinesia, arrhythmias (supraventricular tachycardia, bradycardia), hypertension, hypotension, constipation, diarrhea, dry mouth, nausea, gynecomastia, methemoglobinemia , neutropenia, leukopenia, agranulocytosis Monitor for neuroleptic malignant syndrome (hyperthermia, muscle rigidity, altered consciousness, irregular pulse or BP, tachycardia, and diaphoresis)l Doxylamine- pyridoxine/ Diclegis Antiemetics; decreased nausea and vomiting associated with pregnancy Combination of an antihistamine and a vitamin B6 analog Treatment of nausea and vomiting during pregnancy that has not responded to conservative management Drowsiness Assess for frequency and amount of emesis daily during therapy. Monitor hydration status to prevent dehydration Methotrexate/ Trexall Antimetabolites; antineoplastics; antiheumatics; immunosuppressants Interferes with folic acid metabolism Dissolves ectopic pregnancies; treatment of: trophoblastic neoplasms, leukemias, breast carcinoma, head carcinoma, neck carcinoma, lung carcinoma Arachnoiditis, dizziness, drowsiness, headache, malaise, seizures, blurred vision, dysarthriatransient blindness, pulmonary fibrosis, interstitial pneumonitis, hepatotoxicity, anorexia, diarrhea, nausea, stomatitis, vomiting, acute renal failure, infertility, erythema multiforme, stevens- johnson syndrome, toxic epidermal necrolysis, alopecia, painful plaque Methotrexate dissolves ectopic pregnancies by destroying rapidly dividing cells
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erosions, photosensitivity, pruritus, rashes, skin ulceration, urticarial, aplastic anemia, anemia, leukopenia, thrombocytopenia, hyperuricemia, osteonecrosis, stress fracture, nephropathy, chills, fever, soft tissue necrosis Clomiphene / Clomid Ovulation inducer Stimulates release of pituitary gonadotropins, follicle-stimulating hormone, and luteinizing hormone, resulting in ovulation and the development of the corpus luteum Induces ovulation in anovulatory women who desire pregnancy.
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  • Spring '17
  • Showalter
  • Obstetrics, Opioid receptor

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