glucose-lowering medications. The glucosidase enzyme which is located in the smallintestine (in the brush border) is responsible for the absorption of monosaccharides and thebreakdown of carbohydrates. Although AGIs delay the absorption of ingested carbohydrates,they do not prevent their absorption. As a result, the postprandial glucose and insulin peaks isreduced. According to Bothon et al. (2013), testing the a-glucosidase inhibitory effect of theproject plants might help to understand their mechanisms of action. Kwon et al. (2006), alsoaffirms that the consumption of inhibitors from constituents in the diet could be an effectivetherapy for managing postprandial hyperglycemia. Importantly, the natural consumption ofinhibitors has minimal side effects compared to traditional treatments with drugs such asacarbose.
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Methodology and Result 7For the current time of this project 8 extract of Barbeya oleoides(sample 4, leaves part).The a-glucosidase inhibitory activity of the extract of 8 different solvent were tested. Sample Mean(%inhibition)SD Percentage of errorHexaneChloroform Ethylacetate acetoneMethanol Hot water Ethanol 60 %Cold water Chloroform, acetone, methanol, water and 60% ethanol showing the higher inhibitory effect. Reference List
Methodology and Result 8Bothon, F.T., Debiton, E., Avlessi, F., Forestier, C., Teulade, J.C. and Sohounhloue, D.K.,2013. In vitro biological effects of two anti-diabetic medicinal plants used in Benin asfolk medicine.BMC complementary and alternative medicine,13(1), p.51.CBD. 2002. Saudi Arabia -Status and Trends of Biodiversity [Online]. Available at:<; [Accessed17 November 2017].Kwon, Y.I.I., Vattem, D.A. and Shetty, K., 2006. Evaluation of clonal herbs of Lamiaceaespecies for management of diabetes and hypertension.Asia pacific journal of clinicalnutrition,15(1), pp.107-118.Yuan, T., Wan, C., Liu, K. and Seeram, N.P., 2012. New maplexins F–I and phenolicglycosides from red maple (Acer rubrum) bark.Tetrahedron,68(4), pp.959-964.
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