Creutzfeldt-Jakob Disease bio 181.docx

A cohort study in the united kingdom had the

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A cohort study in the United Kingdom had the objective of finding the early psychiatric and neurological features of various Creutzfeldt-Jakob disease. The study was measuring the timing and nature of the early neurological symptoms in patients, such as dysphoria, withdrawal, anxiety, insomnia and loss of interest. Most of the data concluded that patients exhibit neurological symptoms within 4 months of clinical onset, those including poor memory, pain, sensory symptoms, unsteadiness of gait, and dysarthria (difficult or unclear articulation of speech that is otherwise normal). The study concluded that although the diagnosis of Creutzfeldt-Jakob disease is almost impossible in the early stages of the illness, particular combinations of the psychiatric and neurological features may allow early diagnosis in many patients. (Spencer, Michael D) Works Cited Spencer, Michael D., Richard S. G. Knight, and Robert G. Will. "First Hundred Cases of Variant Creutzfeldt-Jakob Disease: Retrospective Case Note Review of Early Psychiatric and Neurological Features." British medical journal 324.7352 (2002): 1479-82. ProQuest. Web. 20 Nov. 2015. "Creutzfeldt-Jakob Disease." Creutzfeldt-Jakob Disease . Web. 21 Nov. 2015.
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Youtube Videos: Exam questions Which disease is also a prion disease? A. AIDS B. Alzheimer's Disease C. Fatal Familial Insomnia D. Rabies
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What is one of the main symptoms of CJD disease? A. Blood clotting B. Dementia C. Paralysis D. Fatigue Essay Question: Write a paragraph the space below to answer the question using complete sentences. Explain how Creutzfeldt-Jakob disease progresses through the human body ? Rare spontaneous misfoldings cause proteins in the brain to malfunction and become prions. These misfolded proteins infect a brain cell causing it to produce more prions until the brain cell bursts releasing all the prions to infect other brain cells. This is what causes the sponge like appearance and brain damage. If allowed to progress the disease causes the brain to shrink due to loss of brain cells.
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  • Fall '07
  • Bovine spongiform encephalopathy, Prion, Transmissible spongiform encephalopathy, CJD

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