Communication at the Synapse.pptx

5 epsps or ipsps spread toward the postsynaptic axon

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to open and leading to an EPSP or IPSP. 5. EPSPs or IPSPs spread toward the postsynaptic axon hillock—if threshold is reached, an action potential will occur. 6. Synaptic transmission is rapidly stopped —action is brief and accurately reflects the activity of the presynaptic cell.
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Neural Integration Spatial summation = the summing of all the potentials that reach the axon hillock from locations across the cell body. If the overall depolarization—the sum of EPSPs (+) and IPSPs(–)—reaches or exceeds the threshold, an action potential is produced. Temporal summation = the summing of all the potentials that reach the axon hillock based on time of arrival. The closer together in time the potentials arrive, the greater their impact and likelihood of producing an action potential. Excitation from one active synapse can be enough to initiate the formation of an action potential
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Types of synapses: Axo-dendritic —the axon terminal synapses on a dendrite Axo-somatic —synapse between axon and cell body ( soma ) Axo-axonic —synapse between two axons
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  • Spring '18
  • Catherine Diaz-Asper
  • axon terminal, postsynaptic cell, presynaptic cell

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