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potassium. This antibiotic belongs to the penicillin and clavulanate is a beta lactamase inhibitor, which helps to prevent susceptible bacteria form becoming resistant and fights bacteria in the body. Augmentin is used to treat many different infections caused by bacteria, such as sinusitis pneumonia, ear infections bronchitis urinary tract infections and infections of the skin (Augmentin, 2018).Amoxicillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative microorganisms. Dose and regimen include amoxicillin and clavulanate potassium are well absorbed from the GI tract after oral administration of Augmentin. The half-life of amoxicillin after oral administration is 1.3 hours and clavulanic acid is 1.0 hours. Approximately 50% to 70% of the amoxicillin and approximately 25% to 40 % of the clavulanic acid are excreted unchanged in urine during the first 6 hours after administration of a single 250 mg or 500 mg tablet of Augmentin. Augmentin is contraindicated in patients with a history of allergic reactions to any penicillin, patients with a previous history of kidney or liver disease (Amoxicillin, 2016).4.Would this treatment vary if Mr. JD was a 10-year-old 78 lb. child? Include the class of the medication, mechanism of action, dosing, route, the half-life; how it is metabolized inand eliminated from the body; and contraindications and black box warnings.
If Mr. JD were a 10-year-old 78 lb. child, his treatment would vary from adult dosages. Pediatric patients weighing 40 kg, or more should be dosed according to the adult recommendations, but pediatric patients weighing less than 40 mg have not been established. Mr.JD would then be prescribed Amoxicillin. Amoxicillin is active against many gram positive and gram negative bacteria. Amoxicillin acts by inhibiting bacterial cell wall synthesis. Lack of bacterial cell wall results in death due to lysis of bacteria. Amoxicillin is useful for only activity growing and cell wall synthesizing bacteria. The half-life of amoxicillin is 61.3 minutes.