Response Feedback: Chemotherapeutic drugs that are most effective during a particular phase of the cycle are known as cell cycle– (or cell phase) specific, whereas drugs that act independently of a specific cell cycle (or cell phase) are cell cycle–nonspecific. Not all cell cycle–specific drugs achieve a synergistic effect with cell cycle–nonspecific drugs. These drugs are not named because of the particular sequence of cytotoxic events that they cause. Question 5 1 out of 1 points A clinic nurse is planning care for a 68-year-old man who has been on omeprazole (Prilosec) therapy for heartburn for some time. Regarding the patient's safety, which of the following would be a priority nursing action? Response Feedback: All of the options would be appropriate for this patient. However, with regard to the patient's safety and the fact that he is a 68-year-old man and has been on omeprazole therapy for some time, the nurse should be concerned about possible hip fractures. Therefore, the priority action by the nurse should be to coordinate bone density testing. Omeprazole decreases the dissolution and absorption of calcium, which may increase the risk of hip fracture. Men are more likely to have PPI- associated hip fractures than women. Question 6 1 out of 1 points Mesalamine (Asacol) is prescribed for a 22-year-old woman with Crohn disease. The nurse will discuss with the patient the possibility for which of the following adverse effects related to the new drug therapy? Response Feedback: The nurse will explain that one possible adverse effect of mesalamine (Asacol) therapy is hair loss. The nurse will emphasize that the hair
loss is generally mild and transient. Metallic taste, fatigue, and increased appetite are not adverse effects of mesalamine. Question 7 1 out of 1 points A 48-year-old woman who works as an office manager is prescribed metoclopramide (Reglan) for diabetic gastroparesis. The nurse will be sure to assess the patient for Response Feedback: Depression, from mild to severe, including suicidal ideation, has occurred in patients with and without a history of depression who take metoclopramide. Use caution in administering metoclopramide to patients with a history of depression. The nurse should assess the patient for signs of depression and monitor behavior as long as the patient is on the therapy. If the patient has been depressed or is depressed, metoclopramide therapy should be given only if the benefits of the drug outweigh the potential risks from depression. Tachycardia, hypotension, and anemia are not associated with metoclopramide. Question 8 1 out of 1 points A 22-year-old male college senior has lived with a diagnosis of Crohn's disease for several years and has undergone several courses of treatment with limited benefit.
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- Helicobacter pylori