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EEMB_2_Final_Ivory

The safest vaccine virus with respect to preventing

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27. The safest vaccine virus with respect to preventing the vaccine virus from evolving inside a patient’s body to cause AIDS would be: A. The 50 passages virus B. The 100 passages virus C. A modified 100 passages virus that also had had an added mutation in the reverse transcriptase gene that caused a block in its transcription in human CD4 + helper T- cells D. No expected differences between the 50 and 100 passage virus E. Both answers A & C are correct 28. If the 50-passage virus were treated with formalin (as is the injected polio vaccine virus used in developed countries) EEMB 2 Final Ivory Version: 0 Page: 8
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29. Suppose that the vaccine was initially successful, but eventually the HIV virus in nature evolved resistance so that vaccinated people were no longer immune to the virus but in immunized people the virus’ generation time was increased 3-fold. After a vaccinated person became infected, about how long would it take for disease symptoms to occur? 30. If everyone in the world switched to a vegetarian diet for many years (leading to many associated changes in agriculture), then the the frequency of influenza pandemics would be: EEMB 2 Final Ivory Version: 0 Page: 9
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Use the following information for the next 5 questions (until you see a solid line): John Doe is interested in the hereditary basis of susceptibility to a form of a common cold virus. He collected a random sample of people and genotyped them at the D locus for two alleles: D High , which he hypothesizes increases susceptibility to the virus, and D Normal . The sample is tabulated below as the entire sample and also the subset of individuals who had no antibodies to the virus (uninfected). 31. Compared to the entire sample, and based on allele frequencies in the gene pools: A. D High is more common in the uninfected sample by an amount (delta) equal to 0.5 B. D Normal is more common in the uninfected sample by an amount (delta) equal to 0.05 C. D Normal is more common in the uninfected sample by an amount (delta) equal to 0.4 D. D High is more common in the uninfected sample by an amount (delta) equal to 0.4 E. Answers B & D are both correct
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