Lithium is a drug that has been used for a long time to treat the manic phase

Lithium is a drug that has been used for a long time

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Lithium is a drug that has been used for a long time to treat the manic phase of bipolar disorder. What is the primary action of lithium? A. Inhibits the release of serotonin and norepinephrine B. Inhibits the release of serotonin and dopamine C. Inhibits the release of norepinephrine and dopamine D. Inhibits the release of serotonin and second messengers
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Central Nervous System Stimulants Central Nervous System Stimulants Actions CNS stimulants act as cortical and RAS, possible by increasing the release of catecholamines from presynaptic neurons leading to an increase in stimulation of the postsynaptic neurons Indications Treatment attention – deficit syndromes Narcolepsy
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Central Nervous System Stimulants (cont.) Central Nervous System Stimulants (cont.) Pharmacokinetics Rapidly absorbed from the GI tract Peak 2-4 hours Metabolized in the liver Excreted in the urine T ½ 2-15 hours Contraindications Known allergy, marked anxiety, agitation, or tension and severe fatigue or glaucoma
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Central Nervous System Stimulants (cont.) Central Nervous System Stimulants (cont.) Adverse Effects Nervousness, insomnia, dizziness, headache, blurred vision, anorexia, nausea, weight loss Drug-to-Drug Interactions MAOI’ s Guanethidine Tricyclic antidepressants Phenytonin
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Nursing Considerations for Central Nervous System Stimulants Nursing Considerations for Central Nervous System Stimulants Assess: History and Physical Exam Known allergies, glaucoma, Anxiety, tension, fatigue, or seizure disorder; cardiac disease and hypertension; pregnancy or lactation History of leukemia; and a history of drug dependency, including alcoholism Urinary output, VS including lung sounds and CBC
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Question Question Please answer the following statement as true or false. Narcolepsy is thought to be a problem with stimulation of the brain by the reticular activating system.
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Copyright © 2017 Wolters Kluwer • All Rights Reserved END! END!
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