The data recorded from all three phases showed a significantly lower amount of

The data recorded from all three phases showed a

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The data recorded from all three phases showed a significantly lower amount of occurrences of CLASBIs during phase 2 for all 4 hospitals when compared to phase 1 and 3. Only 2 hospitals where able to implement phase two with 100% compliance and even though the data recorded from every hospital was consistent in conclusion, the lack of compliance in using the disinfectant cap would bias the findings. The study is both replicable and generalizable as 4 hospitals associated with the University of Chicago had similar results. Also the design of the study allowed for multiple hospitals used and different phases with different comparisons lending to the reliability of the study and the results.
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Study Citation Design Method Sample Data Collection Data Analysis Validity Reliability Kamboj, M., Blair, R., Bell, N., Son, C., Huang, Y., Dowling, M. & Sepkowitz, K. (2015). Use of Disinfection Cap to Reduce Central-Line–Associated Bloodstream Infection and Blood Culture Contamination Among Hematology–Oncology Patients. Infection Control & Hospital Epidemiology, 36(12), 1401-1408. doi:10.1017/ice.2015.219 The design for this study was that of a multiphase prospective study The method for this study consisted 4 phases. During phase 1 pre intervention was established along with baseline rates. In phase 2 CDC guidelines were followed. Phase 3 is where disinfection cap intervention was implemented in high risk units. Phase 4 is when hospital-wide disinfection caps where implemented on general oncology units. The sample for this study was taken from Memorial Sloan Kettering Cancer Center. This cancer center consists of 470 bed with approximately 23,000 admissions annually. The study sample consisted of all patients with Central lines which is approximately 53% of patients at the hospital. Data was collected from this study at various times for each phase. May 2010 to Aug 2011 – phase 1 & 2. Sep 2011- Mar2012 – phase 2. Apr 2012-Dec 2012 – phase 4. After data collection occurred, data analysis showed that blood culture contamination decrease by 63% in high risk units and 51% in general oncology units during phase 4. It is not possible to determine how much of the reduction rate was attributed to the direct use of disinfection cap. Reduction rate in HRU did not become apparent until phase 4 where caps have been in use for 16 mos. Comparing the result to other studies, the use of disinfection cap demonstrated a reduction in CLABSI and is replicable and generalizable to the larger population.
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  • Summer '17
  • Central venous catheter, Intravenous therapy, Cap, bacteremia

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