Explain the principles behind how different diuretics

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Explain the principles behind how different diuretics work to excrete excess water from the body. o Video Resources : While you don’t need to understand diuretics in depth for this course, looking at how each diuretic impacts the different part of the kidney will help you check your understanding on how the kidney functions. See these video resources: How Diuretics work: USMLE Kaplan Medical: Diuretics: Pharmacology – Diuretics: by Armando Hasudungan: 7.3.3 - Hormonal Regulation of Urine Production Explain the hormonal regulation of urine formation . o Describe each of the three regulatory pathways the kidneys use to reabsorb more water and decrease excretion: Pathway: Osmorecep tors Barorecept ors: decreased blood pressure Barorecept ors: increase blood pressure Renin- Angiotensi n- Aldosteron e System Where are sensors located? What activates this pathway? Which hormones are released from Page 5
BIO 265 where? What part of the kidney is acted on by these hormones? What is the effect on water? Is it excreted or reabsorbed ? What is the overall effect to the body or blood pressure? Renin-Angiotensin-Aldosterone System o Study Tip : Create your own diagram or presentation of the RAAS system. Find a friend and teach them what you have learned! o What does increasing aldosterone do? o What happens if a person has hyperkalemia (High K+)? o Video Resources: Sodium Regulation: Renin-Angiotensin-Aldosterone System: Renin Angiotensin Aldosterone System from Mechanisms in Medicine: Aldosterone compared to ADH by Khan Academy: Hyperkalemia: Hypokalemia: Take BIO 265 Quiz 7.3 Page 6

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