Lecture 12 – Cardiovascular Physiology VII

Osmotic pressure due to plasma protein pulls water

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Osmotic pressure due to plasma protein [], pulls water into capillary Osmotic force from IFS [] Algebraic sum of these forces becomes net filtration pressures 
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Hydrostatic pressure is lower in the venuoles than it is in the arterioles It falls across the capillaries Filtration pressure due to proteins in the ISF is 0 on both the arterial and the venous end NFP = Pc + pi(IF) – PIF – pi(c) Net outward force is greater than the net inward force Veins Smooth muscles, SNS innervation Decrease diameter and compliance of vessel Forces the volume of venous blood towards the heart Goes towards the heart because they only allow one way flow Venous return towards the heart is the only possibility Similar thing when skeletal muscle contraction around the veins Compress the veins and forces blood to heart Respiratory pump Normal respiration – diaphragm contracts and compresses organs Decrease thoracic pressure but increases abdominal pressure Decrease of pressure in the vein and thoracic cavity This will increase pressure gradient between peripheral veins and heart Increases venous return to the heart Increase sympathetic activity of nerves to veins OR increase blood volume OR increase inspiration movements Increase venous pressure Increase venous return Increase atrial pressure Increase EDV
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Increase stroke volume Overview of MAP Regulation MAP is the driving force for blood to all tissues except the lungs MAP is the product of CO and TPR
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