GENETICS
practice questions exam 2.docx

Pedigree 1 may represent autosomal recessive

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Pedigree 1 may represent autosomal recessive inheritance but not autosomal dominant inheritance C. Both pedigrees may represent autosomal dominant inheritance D. Both pedigrees may represent autosomal recessive inheritance E. Pedigree 1 may represent autosomal dominant inheritance and pedigree 2 may represent autosomal recessive inheritance Pedigr ee 1 Pedigr ee 2
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21.The phenomenon in which mutations in a single gene can result in a wide variety of seemingly unrelated phenotypes is referred to as: A. sex-limited inheritance B. overdominance C. quantitative variation D. pleiotropy E. heterozygote disadvantage 22. In a typical Mendelian dihybrid cross AaBb x AaBb, what is the expected proportion of progeny that are A_B_ A. 9/16 B. 3/16 C. 12/16 D. 1/16 E. None of the above 23.Which of the following terms implies that the phenotype of the heterozygote for alleles of an appropriate gene, is dependent upon the sex of the individual: A. Heterozygote advantage B. sex-limited inheritance C. sex-influenced inheritance D. both B and C E. none of the above 24.For a quantitative trait observed in the F2 generation, the number of individuals showing one of the extreme phenotypes was 11 out of a total of 704 F2 progeny. Therefore the number of genes pairs involved in controlling the trait being studied, under the given set of experimental conditions is: A. 1 B. 2 C. 3 D. 4 E. 16
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25.Two individuals with fused earlobes have a child with non-fused ear lobes. Fused earlobe is usually associated with homozygous recessive alleles in either one of two different genes that function in different steps of the same developmental pathway. Both parents are homozygous for the recessive fused ear alleles but in two different genes that control this character. Their child shows non-fused ears due to: A. heterozygous advantage B. quantitative variation C. discontinuous variation D. complementation E. gene redundancy 26. Which of the following two results representing the weight of seeds under the influence of alleles at single gene (W,w) is suggestive of a low environmental influence on the weight: A. A B. B C. Both A and B D. Neither A nor B A B
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27.The dominant lethal Huntington disease allele is maintained in the human population because: A. The heterozygote is much fitter than the wildtype B. The onset of this fatal disease begins in adulthood and individuals may have already passed on the disease allele to their progeny C. Huntington’s disease affects only males D. Huntington’s disease affects only females E. None of the above 28. Individuals heterozygous for the allele die when they consume just 100 ml of beer however if they avoid alcohol they are perfectly healthy and safe. Normal individuals do not die when they consume 100 ml of beer. The allele is therefore a ____________________. A. toxic allele B. semi-lethal allele C. conditional lethal allele D. paradoxical allele E. None of the above is true 29. Two alleles of a gene are A and a. You cross two heterozygous parents Aa to obtain progeny in the following numbers.
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  • Fall '15
  • Gene B, Zygosity, Sex linkage

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