What is the most common cause of acute liver failure and hepatotoxicity 63

What is the most common cause of acute liver failure

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62. What is the most common cause of acute liver failure and hepatotoxicity? 63. Define teratogenic. 64. Define iatrogenic. 65. What are the three most common causes of fatal medication errors? 66. Why are the elderly more sensitive to drugs? 67. A patient with kidney or liver disease would require (higher or lower) dosages of a medicine? 68. Define bioavailability. 69. Define the placebo effect. 70. Define tachyphylaxis. 71. Define tolerance. 4
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72. A patient with glucose-6-phosphate dehydrogenase (G6PD) deficiency that takes aspirin or a sulfanilamide is at risk for what disorder? 73. During pregnancy, increased renal blood flow leads to accelerated excretion of drugs. This process may require (increase or decrease) in drug dosages? 74. What class of blood pressure medication should not be taken during pregnancy? 75. Which FDA pregnancy risk category shows risk of fetal harm in women or animals whereby the risks clearly outweigh any possible benefit? 76. Which antibiotics should not be taken during pregnancy? 77. When is the best time to take a medication if breast feeding? 78. A neonate is defined as (less than or greater than) 4 weeks of age? 79. Protein or albumin is (higher or lower) in and infant which might lead to (increased or decreased) levels of a drug bound to protein? 80. Hepatic metabolism and renal excretion in infants is (high or low)? 81. Why are neonates especially sensitive to drugs that affect the CNS? 82. The rate of drug absorption in the elderly is (slow or accelerated)? 83. Drugs last longer in the elderly due to (decreased or increased) liver function? 84. What is creatinine clearance and why is it important in the elderly? 85. How do you measure and calculate creatinine clearance, and what amount is considered normal? 86. What is the Beers criteria? 1. When a drug activates receptors directly, it is called an (agonist or antagonist)? 2. When a drug mimics the effects of a natural transmitter it (increases or decreases) receptor activation? 3. A drug that promotes transmitter release (increases or decreases) receptor activation? 4. Stimulation of the parasympathetic system has what effect of the following organs: 1. Heart 2. Stomach 3. Bowel and bladder 4. Eye 5
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5. Lung 5. Stimulation of the sympathetic system has what effect on the following: a. Heart rate b. Blood pressure c. Skin d. Bronchi e. Pupils f. Glucose levels
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