Blood types are determined by surface antigens on erythrocytes 3 alleles

Blood types are determined by surface antigens on

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Blood types are determined by surface antigens on erythrocytes 3 alleles possible to code for type of glycoprotein on outside surface of RBC
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BIOL 4160 Exam 3 Problem with someone who is type A receiving type B blood?
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BIOL 4160 Exam 3 Activation of thrombocytes results in release of: *Thromboxane A2 * - results in further aggregation of platelets to injured area – amplified signal ADP – travels to normal endothelium cells on either side of injury – release prostacyclin and nitric oxide, which prevents formation/aggregation of platelets in normal tissue/endothelium o 3 – Blood coagulation Platelet plug formation review Area of trauma exposes collagen VW circulating in plasma binds at that site VW attracts thrombocytes to the site and activates them – now spiky matrices Activation of thrombocytes results in the release of: o Thromboxane A2 – further aggregation of platelets at injured site o ADP – normal endothelium releases prostacyclin and nitric oxide, which prevents aggregation of platelets in normal tissue (targets platelet formation at area of injury) Medical relevance Aspirin Inhibits the formation of prostaglandins such as thromboxane A2 At risk of bleeding out o Inhibiting clot formation NSAIDs (non-steroidal anti-inflammatory drugs) Also ibuprofen and acetaminophen – not as big of a problem as aspirin Blood clot formation
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BIOL 4160 Exam 3
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