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Encourage patient to comply with additional therapies prescribed for muscle spasm (rest, physical therapy, heat, etc). If musculoskeletal discomfort persists consult health care professional for further evaluation. May cause dizziness or drowsiness. Advise patients to avoiddriving or other activities requiring alertness until response to drug is known. Instruct patientto change positions slowly to minimize orthostatic hypotension.Brand Name and Generic NameNormal Dosage RangesContraindicationsEntresto (Sacubitril/Valsartan)Initial dose — sacubitril 49 mg/valsartan 51 mg twice daily, dose may be doubled every 2 – 4 weeks to target dose of 97mg/valsartan 103 mg as tolerated.Sacubitril 24 mg/ valsartan 26 mg,Hypersensitivity or history of angioedema from previous ACE inhibitors or ARBs; Concurrent useof ACE inhibitors during or for 36 hours before or after; Concurrent use with aliskiren in patients with diabetes or moderate-to-severe renal impairment (CCr >60 mL/min); Severe
Medicationssacubitril 49 mg/valsartan 52 mg, sacubitril 97 mg/valsartan 103 mg. hepatic impairment; Use Cautiously in: HF (mayresult in azotemia, oliguria, acute renal failure and/or death); Volume- or salt-depleted patients or patients receiving high doses of diuretics (correct deficits before initiating therapy or initiate at lower doses).Pharmacotherapeutic ClassDosage OrderedAdverse ReactionsTherapeutic: vasodilators, antihypertensives Pharmacologic: angiotensin II receptor antagonists, neprilysin inhibitors 24mg-26mg Dizziness, cough, hypotension, hyperkalemia, ANGIOEDEMA. Why is patient receiving this med? (Can list related diagnosis, symptom, or need)Route and FrequencyNursing Considerations and TeachingReduced cardiovascular death and hospitalizations due to HF. 1 tab PO dailyInstruct patient to take Entresto as directed, at the same time each day, even if feeling well. Take missed doses as soon as remembered if not almost time for next dose; do not double doses. Warn patient not to discontinue therapy unless directed by health care professional. Advise patient to read Patient Information before starting therapy and with each Rx re- fill in case of changes. Caution patient to avoid salt substitutes containing potassium or foods containing high levels of potassium or sodium unless directed by health care professional. Brand Name and Generic NameNormal Dosage RangesContraindicationsAspirin (acetylsalicylic acid, Acuprin, ASA, Aspir-Low, Aspirtab, Bayer Aspirin, Bayer Timed-Re- lease Arthritic Pain Formula, Easprin, Ecotrin, 8-Hour Bayer Timed-Release, Empirin)81 mgOTC, 162.5 mgOTC, 325mgOTC, 500 mgOTC, 650 mgOTCHypersensitivity to aspirin or other salicylates; Cross-sensitivity with other NSAIDs may exist (less with non-aspirin salicylates); Bleeding disorders or thrombocytopenia; May increase risk of Reye’s syndromein children or adolescents with viral infections. Use Cautiously in: Patients with a history of GI bleeding or ulcer disease; Chronic alcohol use/abuse; Severe hepatic or renal diseasePharmacotherapeutic ClassDosage OrderedAdverse ReactionsTherapeutic: antipyretics, nonopioid