a.congenital immunodeficiency2.What two types of patients help demonstrate that cancer can be considered a failure of the immune system?a.transplant patients and HIV/AIDS patients3.Which of the following class of hypersensitivity reactions is not associated with autoimmunity?a.Allergies4.Which of the following statements best describes the hygiene hypothesis as it relates to allergies?a.As a result of increased antibiotic usage and cleaner foods and beverages, our normal gut microbiota has shifted, resulting in increased hypersensitivities in developed countries.5.Which of the following statements concerning desensitization therapy is true?a.Desensitization therapy encourages plasma cells to produce IgG antibodies against the allergen.6.Which of the following factors impacts the signs, symptoms, and severity of an allergic response?a.family history, route of exposure, and IgE production7.What is the difference between an intolerance and an allergy?a.Intolerances tend to have a delayed onset of symptoms, while allergic reactions occur rapidly.8.Which of the following allergies and treatments is mismatched?
a.insect bite/sting allergy: continued preemptive treatment with an injected antibody preparation that ties up the patient's IgE antibodies9.In desensitization immunotherapy, an antigen is used to stimulate cell 2, which can then stimulate cell 3 and cause the production of item 4. Identify cell 2, cell 3 and item 4.a.T regulatory cell, T helper 1 cell, and IgG antibodies10.Desensitization immunotherapies are least effective to treat allergies from which of the following?a.Milk11.Which of the following type II hypersensitivities is noncytolytic?a.Grave's disease12.Following a blood transfusion, your patient has disseminated intravascular coagulation and is experiencing hypotension (low blood pressure), tachycardia (increased heart rate), and low platelet count. During a blood typing analysis, you observed that this patient's blood had reactedwith purified A antibody and Rh antibody, but not with purified B antibody. Based on this information, which of the following blood types was most likely given to the patient to result in this type II hypersensitivity?a.AB+13.Graves' disease is an example of which of the following type II hypersensitivity cytotoxic reactions?a.Antibodies interact with a cell-surface receptor on self-cells causing the overactivation ofthe receptor.14.Which of the following examples of type II hypersensitivities are matched incorrectly with their mediated mechanism?a.Goodpasture syndrome: noncytolytic15.In what situation is hemolytic disease of the newborn a life and death situation?a.when an RH- mom is pregnant for the second time with an RH+ fetus16.Which of the following diseases makes antibodies against centromeres and topoisomerases?