Dust Bacteria Fungi Farmers Lung is a hypersensitivity pneumonitis induced by

Dust bacteria fungi farmers lung is a

This preview shows page 31 - 38 out of 38 pages.

DustBacteria, Fungi, Farmer’sLung (is a hypersensitivity pneumonitis induced by the inhalation of biologic dusts coming from hay dust or mold spores or other agricultural products.Pigeon Breeder’sLung, caused the exposure to avian proteins present in the dry dust of the droppings and sometimes in the feathers of a variety of birds.
Image of page 31
NON-Caseating Granulomas are the RULE “Asteroid” bodies within these granulomas are virtually diagnostic, but hard to find Note: sarcoidosis is NOT limited to the lungs.
Image of page 32
3. SMOKING RELATED DIP ( D esquamative I nterstitial P neumonia) because it looks like the alveolar wall “epithelium” is peeling off into the alveolus M>>F CIGARETTES 100% Survival Alveolar Macrophages
Image of page 33
4. PAP (Pulmonary Alveolar Proteinosis ) Very RARE, usually acquired Proteinaceous Material in Alveoli MINIMAL cellular inflammatory infiltrate Like Pulmonary Edema, but MUCH Protein
Image of page 34
2. Extrinsic disorders of restrictive lung diseases Are extra-pulmonary diseases due to Diseases of the chest wall, Disease of the pleura, Damage to the nerve Damage to the respiratory muscles They resulted in lung restriction, impaired ventilatory function respiratory failure (eg, non-muscular diseases of the chest wall, neuromuscular disorders ).
Image of page 35
Image of page 36
VASCULAR PULMONARY DISEASES THREE TYPES 1. PULMONARY EMBOLISM (with or usually WITHOUT infarction) 2. PULMONARY HYPERTENSION , leading to cor pulmonale 3. HEMORRHAGIC SYNDROMES GOODPASTURE SYNDROME HEMOSIDEROSIS , idiopathic WEGENER GRANULOMATOSIS
Image of page 37
Pulmonary Embolism Usually secondary to debilitated states with immobilization, or following surgery Usually deep leg and deep pelvic veins (DVT), NOT superficial veins Follows Virchow’s triad, i.e., 1) flow problems, 2) endothelial disruption, 3) hypercoagulabilty Usually do NOT infarct, usually ventilate When they DO infarct, the infarct is hemorrhagic Decreased PO2, acute chest pain, V/Q MIS-match DX: Chest CT, V/Q scan, angiogram RX: short term heparin, then long term coumadin
Image of page 38

You've reached the end of your free preview.

Want to read all 38 pages?

  • Fall '19

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture