Part c the pathway of secretory proteins proteins

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Part C ­The pathway of secretory proteinsProteins that are secreted from a eukaryotic cell must first travel through the endomembrane system.Drag the labels onto the diagram to identify the path a secretory protein follows from synthesis to secretion. Not all labels will be used.Hint 1.How to approach this problemNot all of the labels will be used in the flowchart. Review the functions of each organelle listed and eliminate the organelles not involved in thesynthesis, modification, or transport of secretory proteins. Then place the remaining organelles in the correct order.Hint 2.Where are the organelles of the endomembrane system located?Knowing the structure and locations of the compartments that make up the endomembrane system can help you understand how substances movewithin and between the organelles.Drag the labels to their appropriate locations on the diagram.ANSWER:Hint 3.How does cargo move through the Golgi?Complete this sentence.
Cargo leaves the endoplasmic reticulum and is sent to the _____ Golgi cisterna, which then matures through the redistribution of enzymes tobecome a _____ Golgi cisterna and eventually the _____ Golgi cisterna.
Part D ­Pulse­chase experiments and protein locationScientists can track the movement of proteins through the endomembrane system using an approach known as a pulse­chase experiment. Thisexperiment involvesthe “pulse” phase: Cells are exposed to a high concentration of a radioactively labeled amino acid for a short period to tag proteins that arebeing synthesized.the “chase” phase: Any unincorporated radioactively labeled amino acids are washed away and large amounts of the same, but unlabeled,amino acid are added.Only those proteins synthesized during the brief pulse phase are radioactively tagged. These tagged proteins can be tracked through the chase period todetermine their location in the cell.The data below were obtained from a pulse­chase experiment in which cells were examined at different times during the chase period. The numbers

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