Lecture 24 — Motivation.pdf

Hippocampus in the plus maze mark packard and james

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Caudate v. Hippocampus in the Plus Maze Mark Packard and James McGaugh Start Here Food After N days of training ? ? Start Here Training Trial Test Trial
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Caudate v. Hippocampus in the Plus Maze Mark Packard and James McGaugh Start Here “Place” Strategy “Response” Strategy
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How does dopamine contribute to motivation?
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Neuroleptics attenuate ICSS From R.A. Wise (2004) Runway with brain stimulation lever at the end Lever press rate Start box Run ! Press
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Neuroleptics attenuate ICSS From R.A. Wise (2004) Runway with brain stimulation lever at the end Running Speed Lever press rate Start box Run ! Press
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Neuroleptics attenuate ICSS From R.A. Wise (2004) Runway with brain stimulation lever at the end Latency to leave start box Running Speed Lever press rate Start box Run ! Press
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Dopamine cells fire in response to unexpected rewards Wolfram Schultz
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During training: (i.e., reward is surprising) After training: Surprising nonreward
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The basal ganglia include multiple parallel loops with distinct functions The loops have different cortical starting and end points, but otherwise the architectures are quite similar.
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Huntington’s chorea
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Huntington’s chorea
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Parkinson’s OFF-ON L-DOPA
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Parkinson’s OFF-ON L-DOPA
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  • Spring '16
  • Colgin
  • Substantia nigra

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