E55-2010 problem set 01 KEY

This scenario once the eye progenitor was removed

Info icon This preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
this scenario, once the eye progenitor was removed, this absence was ‘sensed’ in some manner by the embryo and led to regulatory events that effectively replaced the missing tissue. A mosaic mechanism would be suggested if removal of the eye progenitor at this particular developmental stage led to an absence of an eye; in this case, the future eye is autonomous from the rest of the embryo, suggesting that only the eye progenitor is capable of becoming eye (perhaps through the inheritance of particular determinants). 6. What technology could you use to test if your chosen eye progenitor gene is necessary for eye formation. Clearly state one possible phenotype that you would predict if your eye is necessary, one possible phenotype if your gene is not necessary. You could knockdown the eye progenitor gene using a technology such as antisense morpholino knockdown. To do this you would inject the morpholino oligonucleotide into the fertilized embryo and then look at the effect on eye development. If your gene is necessary, you might expect to find that the eyes of injected embryos fail to form; conversely, if your gene is not necessary, you might expect to see that eye development is completely normal.
Image of page 1
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern