Cushings triad are three classic signs seen when

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Cushing’s Triad: are three classic signs seen when brain herniation is imminent and include (1) Hypertension (with a widening pulse pressure) (2) Bradycardia (3) Irregular respirations Herniation Transtentorial Herniation: cerebral hemispheres, diencephalon, midbrain is displaced downward affection blood flow and CSF; RAS and respirations affected Uncal herniation: uncus of the temporal love is displaced downward and pressure is exerted against CN III, the posterior cerebral artery, and the RAS Infratentorial (cerebral, or tonsillar) herniation: cerebellar tonsils are pushed downward through the foramen magnum compressing and vital centers causing death Diagnostic tests: CT scans, MRI, cerebral angiography, Doppler ultrasound, EEG, radionuclide (used to track perfusion in CNS) and lumbar puncture (used to check pressure and analyze CSF) Guillain-Barre -Happens after swine flu vaccination, and flu -Ascending paralysis is the symptom that will kill you Guillain-Barre Syndrome Post infection polyneuritis, acute idiopathic polyneuropathy, acute infections Inflammatory conditions of the PNS Precise cause is unknown Local inflammation with accumulated lymphocytes, demyelination, axon destruction (these changes cause impaired nerve conduction) Critical period develop- ascending paralysis involves the diaphragm and respiratory muscles Progressive muscle weakness, lack of reflex response, ascending flaccid paralysis, pain, and generalized muscle aching o Paralysis may move upward- vision and speech may be impaired o Process may occur rapidly over hours or days o Life-threatening situation may develop Treatment is primarily supportive Reye’s Syndrome Affects the brain and the liver, affects the children, caused by aspirin if given during a viral infection destroys the liver Cause is not fully determined Linked to viral infection in children treated with aspirin Manifestations vary in severity No immediate cure Pathologic changes in brain and liver Brain function severely impaired due to cerebral edema Live r enlarged, develops fatty changes in tissue- can cause acute failure Herpes Zoster (Shingles)
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Someone who has chicken pox can get shingles in the future, you can give chicken pox to anyone who hasn’t been vaccinated Herpes zoster (shingles) Caused by varicella-zoster virus in adults can show up years after the primary infection of the varicella Usual affect on cranial nerve or one dermatome Pain, paresthesia, vesicular rash (if the antiviral drugs started within 48 hours of onset, pain will be significantly reduced) Lesions and pain persist for several weeks and in some cases post herpetic pain may persist for several to years in some cases Vaccine available for 60 years old and older Tetanus Caused by clostridium tetany Spore can survive in the soil for years Wound Exotoxin enters the nervous system and causes: Tonic muscles spasms, jaw stiffness Difficulty swallowing, and a stiff neck
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