Species specific fusion of gametes Attraction Acrosomal reaction sperm egg

Species specific fusion of gametes attraction

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Species specific fusion of gametes Attraction, Acrosomal reaction, sperm-egg contact Prevention of polyspermy Activation of egg metabolism Sea Urchin vs. Mammals
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Figure 7.1 Modification of a germ cell to form a mammalian sperm
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Figure 7.2 Structure of the sea urchin egg at fertilization Contents --- Maternal contribution Proteins such as yolk rRNA and tRNA Immediate translation after fertilization mRNA--- a source of morphogens and others Morphogenetic factors (morphogens and determinants) Protective chemicals ECM ECM
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Figure 7.3 Stages of egg maturation at the time of sperm entry in different animal species AKA, Secondary oocyte
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Contents of sea urchin cortical granules Proteolytic enzymes and peroxidases Mucopolysaccharides Adhesive glycoproteins Hyalin protein Figure 7.4 Sea urchin egg cell surface Extracellular envelope -- sperm recognition
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Figure ? The ovarian follicle of mammals Mammalian Oogenesis Go to Fig. 7.5
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Extracellular envelope
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Four major steps in fertilization Attraction Acrosome reaction --- Digestion of outer layer of the egg Binding and penetration of the sperm to extracellular matrix (envelope) of the egg Fusion of egg and sperm cell membranes
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Figure 7.6 Summary of events leading to the fusion of egg and sperm cell membranes in the sea urchin fertilization When does the acrosome reaction occur in sea urchin fertilization? Thick and tough jelly layer Thin vitelline envelope The acrosomal vesicle contains enzymes to digest extracellular matrix. Sperms
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Sea Urchin fertilization Attraction F M Long distance Chemoattraction
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Figure 7.7 Sperm chemotaxis in the sea urchin Arbacia punctulata Key chemoattractant --- sperm-activating peptides Resact (14 a.a.) from jelly coat Resact also activates sperm motility.
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Figure 7.8 Model for chemotactic peptides in sea urchin sperm RGC: Receptor guanylyl cyclase Ca 2+ channel Concentration of free Ca 2+ in sperm cytoplasm tail movement
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  • Spring '19
  • Sperm, Gamete, Spermatozoon

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