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Dose titration is guided by clinical response blurred

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Dose titration isguided by clinicalresponse.blurred visionor eye pain,contact doctorimmediately.mood changes,signs ofdepression.Serum druglevels, sodiumand bicarblevels,electrolytes andammonia ifthere is mentalchangeacutemyopia andangleclosureglaucoma,suicidebehaviors,ataxia,paresthesia,dizziness,somnolence, anddifficultyconcentrating, weightloss, kidneystonesRare:oligohidrosis (decreasedsweating)andhyperthermia
Lithobid,EskalithLithiumreplacessodium duringdepolarizationin neuronalpathways,effectivelystopping thetransmission ofelectricalimpulses.Additionally, itis suspectedthat lithiumacts on thesecondmessengersystempostsynaptically to inhibiteither theinositolmonophosphatase enzyme tomodulate the Gproteins or themessengerRNA to alterthe proteinkinase CTreatment ofmanic phase ofbipolardisorders andprevention ofmanic episodesAcute mania: 600 mgtid or 900 mg bidExtended releaseMaintenance: 300mg tid qid or 450 mgbid controlledreleasetremors,nausea, anddrowsiness maybe signs oftoxicity. Bloodlevels should beobtained 14days afterbeginningtreatment and14 days afterevery dosagechange.Generally,routine bloodlevels areobtained every3 to 6ine tremorsof thefingers,nausea, drymouth,headache,anddrowsiness.Lithium maybe takenwith food tominimize GIdistressSerious:coarsetremors ofthe handsthat impairfunction,nausea andvomiting,diarrhea,confusion,stupor,polydipsiaandpolyuria,muscleweakness,and ataxiaValproateDepakoteblocks GABAuptake intopresynapticneuronswithoutaffecting thebenzodiazepinebinding site. ItComplexpartial, simple(petit mal),absence seizureepilepsy; mania;migraineheadacheInitial 250 mg bid;may increase 125–250 mg weeklyCBCs andserum levels 50-125mcg/mLMild: GIdistress,heartburn,and CNSdepression
appears toenhance GABAfunction,thereby slowingdownrepolarizationand reducingglutamatefunctioning atthe sodium andcalciumchannelsBenzodiazepineXanaxAlprazolaminhibiting GABAis to slow downneurotransmission and therebyproducereduction inanxiety.Serotonin as anNT has acalming effectas well, owingto the areas ofthe brainAnxietydisorder, panicdisorderAnxiety: 0.25–0.5 mgtid, maximum 4mg/dPanic disorder: 0.5mg tid, titrate q 3–4d to 1–10 mg/d(mean 5–6 mg/d)Wean off slowlywhen discontinuingLiver functionand CBCParadoxicalanxiety,agitation,and acuterageAzapironeBuSparBuspironepresynaptic 5-HT 1a receptor,buspirone is afull agonist;contributes tothe channel’sopening andpermittingserotoninbinding,therebyanxietyInitial: 5 mg BID orTID 4 daysincreased by 5 mgeach dose to amaximum dose of 60mg per dayMedicationseffectivenessand moodlight-headedness,headache,insomnia,nausea,nervousness, and drymouth.

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Term
Spring
Professor
Henrikson,J
Tags
Atherosclerosis

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