I really enjoyed your post this week on OA. In a study completed by Kriekova, et al., (2018): OA in females, showed a higher percentage of CD4 + T cells ( P = 0.023) was associated with down-regulated expression of HLA-DR ( P = 0.031) compared to males. We actually see more women affected with RA versus OA. I have honestly seen more males than females in the hospitals here due to the sheer amount of building contractors in this area. These men are so hard on their bodies that by the time they reach their 50’s they are beaten down with OA and have an undue amount of pain. Though OA is known as the “gradual wearing down or old age” arthritis, these contractors have taken it a whole new level, but it is not just the contractors, it’s also rodeo competitors and anyone else that has an active type of lifestyle or job. As you said, OA is generally treated with Tylenol and NSAIDs, but can also be treated with Cymbalta for those that have major issues with their chronic pain and any depression that may be seen due to their younger age and the quicker break down of their bodies (Mayo Clinic, 2018). References Kriekova, E., Manukyan, G., Mikulkova, Z., Gabcova, G., Kudelka, M., Gajdos, P., & Gallo, J. (2018). Gender-related differences observed among immune cells in synovial fluid in knee osteoarthritis. Osteoarthritis and Cartilage.
Mayo Clinic. (2018). Osteoarthritis. Retrieved July 7, 2018 from - treatment/drc-20351930
- Summer '15
- Mayo Clinic, Fibromyalgia, Hashimoto's thyroiditis