Maximum atmospheric concentration or maximum

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Maximum Atmospheric Concentration or Maximum Allowance Concentration (MAC): is the concentration of a toxicant in air (or water) below which deleterious effects are insignificant for eight hours a day, five days a week over a working lifetime. Maximum Permissible Level (MPL): is the limit of radiation or isotope exposure below which one is unlikely to see serious deleterious effect over a lifetime exposure. Median Lethal Dose (LD50): is the dose of a toxicant at which 50% of the population of same specie dies within a specified time and under the specified conditions of the experiment. Median Toxic Dose (TD50): is the dose of a toxicant which causes 50% toxic response point in a specified population and conditions. Pharmacoenvironmentology: is the study of the interaction between drugs and the environment in terms of benefit and risk or it is the study of the effects of drugs on the environment in order to safeguard our environment. The study allows a comprehensive risk assessment of pharmaceuticals on our environment. Poisons or toxicants: are drugs that produce harmful effects when given at a certain dose or circumstance. Pollutant: this is a substance that occurs in the environment, at least in part as a result of human activity, and which has a deleterious effect on living organisms. Risk is the expected frequency of the occurrence of an undesirable effect arising from exposure to a chemical or physical agent. Route of exposure is the route of entry for chemicals into the body. Safety officer: this is a personnel that instigates or enforces a code of practice in the conduct of safety for the work place. Sub acute toxicity: this is lesser intense than acute effect and is produced after repeated exposure over a short period of time (within 1 month). Sub chronic toxicity: this is produced after repeated exposure over a period of 1 -3 months.
203 Systemic toxicity: is the toxic effect that required the absorption and distribution of the toxicant to a part distant from site of entry where effects are produced. Teratogenicity: is the ability to cause toxic effects to the unborn offspring. Threshold Limit Value (TLV): is the maximum concentration of chemical the body can tolerate without having its toxic effect. Threshold Limit Value Short Term Exposure Limit (TLV-STEL): is the maximum concentration that should not be exceeded at any time during a 15-minute exposure period. Threshold Limit Value-Ceiling (TLV-C): is the concentration of chemical that should not be exceeded even instantaneously. Threshold Limits Value Time -Weighed Average (TLV-TWA): is the concentration for a normal 8-hour workday or 40-hour workweek to which workers may be repeatedly exposed without adverse effect. Toxicity: this is the capacity of a chemical agent to cause injury.

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