A bacteriophage that infects escherichia coli o157h7

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A bacteriophage that infects Escherichia coli O157:H7, a cause of foodborne illness. The "O" in the name refers to the cell wall antigen number, whereas the "H" refers to the flagella antigen. Q: What is an antigen? Phage Therapy: - Phages in general have been investigated as medical therapy for disabling bacteria that cause human illness, since phages are much more specific than antibiotics. - Human Volunteers Receiving Escherichia coli Phage T4 Orally: a Safety Test of Phage Therapy ” by Anne Bruttin & Harald Brüssow, American Society for Microbiology, 2005. Images: 2D and 3D diagram of phage , Adenosine; Phage therapy used against Bacillus anthracis , US Gov From the Virtual Microbiology Classroom on ScienceProfOnline.com
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Disease, Please : ______, ______ & ________ ( German Measles) Caused by enveloped ssRNA viruses Common childhood infectious diseases before widespread vaccination. If contract as an adult, illness is more severe. All three are highly contagious, spread by air-borne droplets. MMR vaccine is given 2x in childhood and once in adulthood. Measles: Classic symptoms include 3 day fever, itchy rash, and the three C’s: coughing, coryza (runny nose), and conjunctivitis (red eyes). Mumps: Painful swelling of the salivary glands with fever. Testicular swelling and rash may also occur. Rubella (German measles) : Symptoms usually mild; similar to flu, plus a rash that starts on face and spreads to trunk and limbs. Can cause birth defects if mother contracts rubella during pregnancy. Images: Boy with mumps, PHIL #130; Rubella rash, PHIL #712 From the Virtual Microbiology Classroom on ScienceProfOnline.com
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Meet the Microbe: _______ Nonenveloped dsDNA virus Highly contagious sexually transmitted infection caused by several sub-types of the human papilloma virus . Many types of HPV. Most harmless, but some cause genital warts, and a subset of those can cause cancer: of cervix, vulva and vagina in women; anus and penis in men. Can also cause cancers of head, neck and anus. Genital warts often occur in clusters and can be very tiny or can spread into large masses in the genital area. Two vaccines are available to prevent infection by some HPV types: Gardasil (Merck) and Cervarix (GlaxoSmithKline). Article HPV “ Vaccine Works for Boys: Study Shows First Clear Benefits ”, Science News, Feb. 2011. Images: Papillomavirus , Laboratory of Tumor Virus Biology From the Virtual Microbiology Classroom on ScienceProfOnline.com Centers for Disease Control HPV vaccine Q & A
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Hidden Viruses _____________ Bacteriophage DNA becomes integrated into DNA of host bacteria. ____________ When animal viruses remain dormant in host cells. May be prolonged for years with no viral activity, signs, or symptoms. Some latent viruses do not become incorporated into host chromosome. When viral DNA is incorporated into host DNA, condition is permanent; becomes permanent physical part of host’s Hidden viral DNA is known as a _________ . Image: Bacteriophage Lysogenic Replication , Suly12 Wikimedia Commons; Varicella zoster Herpesvirus, PHIL 1878. From the Virtual Microbiology Classroom on ScienceProfOnline.com
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Genetic instructions of all living things are encoded in the nucleic acid DNA .
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