BIBC 100 WI2011_Midterm 1

2 pts b what is the general function of myoglobin and

Info iconThis preview shows pages 6–9. Sign up to view the full content.

View Full Document Right Arrow Icon
(2 pts) b. What is the general function of myoglobin and hemoglobin? (3 pts) c. Which group(s) below best describes the α -domain structure of myoglobin and hemoglobin? (3 pts) Group 1: “knobs in holes” packing No active site Heptad repeat Leucine zipper Group 2: Highly conserved motif but not highly conserved primary sequence Eight-helix bundle Active site Hydrophobic core Group 3: Four-helix bundle Soluble in an aqueous environment Active site in loop region Heptad repeat Group 4: Eight-helix bundle All α -helices have the same number of amino acids Highly conserved primary sequence Consecutive helices found next to one another in 3D space
Background image of page 6

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
BIBC 100 Name: _______________________ Winter 2011 Midterm/Montal 7 6) a. On the Ramachandran Plot, label the x and y- axis. (2 pts) b. You are given a new Ramachandran Plot with dots in regions not covered in the above plot. Which amino acid does this result represent? (3 pts) c. What type of structure would be in the lower left quadrant? Upper left quadrant? (3 pts) d. What is the reason why not all combinations of angles are allowed? (4 pts)
Background image of page 7
BIBC 100 Name: ___________________ Winter 2011 Midterm/Montal 8 7) Although DNA is a stable structure, it is flexible and offers many sites for binding to regulatory proteins. However, this DNA-protein interaction is very specific. The following image illustrates one way of accomplishing this task: a) What DNA-binding motif is shown? Circle the components of the motif on the diagram. (4 pts) b) What part of the motif is responsible for identifying operator regions on DNA? Describe how this part interacts with DNA and the importance of its distance from the other components of the motif. Assemble adenosine and amino acid Gln together and draw the specific bonds as dashed lines. (You must draw the structure of Gln which is intentionally not given). (5 pts)
Background image of page 8

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 9
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page6 / 11

2 pts b What is the general function of myoglobin and...

This preview shows document pages 6 - 9. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online