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Copyright © 2017 Wolters Kluwer • All Rights Reserved
Question
Question
Please answer the following statement as true or false.
The loop diuretics cause the body to excrete a copious
amount of potassium-rich urine.

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Copyright © 2017 Wolters Kluwer • All Rights Reserved
Osmotic Diuretics
Osmotic Diuretics
•
Pull water into the renal tubule without
sodium loss.
–
Mannitol ( Osmitrol )

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Osmotic Diuretics
Osmotic Diuretics
•
Actions
–
Pull water into the renal tubule without sodium
loss
•
Indications
–
Increased cranial pressure or acute renal failure due
to shock, drug overdose, or trauma
•
Pharmacokinetics
–
Freely filtered at the renal glomerulus, poorly
reabsorbed by the renal tubule
–
Not secreted by the tubule
–
Resistant to metabolism

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Osmotic Diuretics (cont.)
Osmotic Diuretics (cont.)
•
Contraindications
–
Renal disease and anuria
–
Pulmonary congestion
–
Intracranial bleeding, dehydration
–
CHF
•
Adverse Effects
–
Related to sudden drop in fluid levels
–
Nausea, vomiting, hypotension, light-headedness,
confusion, and headache

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Prototype Osmotic Diuretics
Prototype Osmotic Diuretics

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Prototype Osmotic Diuretics (Continued)
Prototype Osmotic Diuretics (Continued)

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Question
Question
How do carbonic anhydrase inhibitors work?

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Nursing Considerations for Diuretics
Nursing Considerations for Diuretics
•
Assess:
–
History and Physical Exam and known allergies
–
Fluid or electrolyte disturbances, gout, glucose
tolerance abnormalities, SLE
–
Hyperparathyroidism and bipolar disorder
–
Skin, edema, cardiopulmonary status, weight, I&O
–
Liver status and appropriate lab values

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins
Chapter 52:
Drugs Affecting the Urinary Tract and
the Bladder
Chapter 52:
Drugs Affecting the Urinary Tract and
the Bladder

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CASE STUDY
CASE STUDY
•
Nursing students need to know
information about drugs affecting the
urinary tract and bladder because in
the United States, only respiratory tract
infections occur more frequently than
acute urinary tract infections.

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•
Form a group of at least 5 members each.