Patients should be told to use adequate contraception and to advise their physician if they become or intend to become pregnant during sibutramine therapy. It would not be appropriate to tell the patient to abstain from sex, and a pregnancy test would not be necessary once a month. However,it would be advisable to have a pregnancy test before therapy begins if the patient is unsure if she is pregnant or if the patient has irregular menstrual periods. A pap smear is not necessarily related to the use of sibutramine but should be done on a regular basis as a normal disease-prevention measure for women.Question 401 out of 1 pointsA 15-year-old boy who has been taking dextroamphetamine for the treatment of ADHD has been experiencing a depressed mood and a sense of hopelessness. He confides in the school nurse that he has begun taking his stepfather's antidepressant to improve his mood. After immediately phoning the boy's stepfather, the nurse learns that the drug in question is phenelzine (Nardil), a monoamine oxidase inhibitor (MAOI). The nurse should recognize that this combination of drugs creates a serious risk of what health problem?
ResponseFeedback:Because of its pressor effects, dextroamphetamine is contraindicated during the first 14 days after discontinuing monoamine oxidase inhibitor (MAOI) therapy, because MAOI therapy itself may predispose the patient toward elevated bloodpressure. Therefore, this 14-day washout period for MAOIs must be observed to prevent hypertensive crisis. This particular combination of drugs does not constitute a risk for a dysrhythmias, kidney damage, or electrolyte imbalances.
- Fall '13
- Pharmacology, Adverse drug reaction, Dextroamphetamine