water hydration during therapy report if signs of renal impairment proper pain

Water hydration during therapy report if signs of

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water (hydration during therapy), report if signs of renal impairment; proper pain management for zoster Annual vaccination for 6 months + Anthelmintics Pharmaco -dynamics Intestinal nematodes are treated with mebendazole, pyrantel, and thiabendazole. Tissue nematodes are treated with mebendazole, thiabendazole, albendazole, or ivermectin. ADRs Nausea, vomiting, diarrhea, transient abdominal pain Mebendazole may cause transient neutropenia. Ivermectin may cause Mazzotti reaction. Clinical use and dosing Pinworms: single dose of mebendazole, pyrantel pamoate, or albendazole Whipworms: pyrantel pamoate, albendazole, mebendazole Roundworms: mebendazole
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Hookworms: pyrantel pamoate, albendazole, mebendazole Threadworm: ivermectin or thiabendazole Scabies: off-label ivermectin in immunocompromised patients Monitorin g Assess for the eradication of the helminth. Roundworms, hookworms, ascariasis, trichuriasis, and whipworms; stool samples are obtained before and 1 to 3 weeks after treatment for proof of cure Patient education Albendazole and mebendazole are given with a high-fat meal. Ivermectin is taken on an empty stomach. Albendazole should not be taken if pregnant and back-up contraception should be used for 1 month after taking. Metronidazole, Nitazoxanide, & Tinidazole Metronidazole Tx of bacterial & parasitic infection Active against Trichomonas vaginalis, Entamoeba histolytica, H. pylori, Clostridium, C. difficile well-absorbed orally Nitazoxanide treat Giardia lamblia and Cryptosporidium. Tinidazole active against amebiasis, giardiasis, and trichomoniasis. Precautio n History of blood dyscrasias, seizure disorder or neurological problems, severe hepatic dysfunction Contra- indication Metronidazole: Pregnancy C (left palate for exposure during the first trimester) treat trichomoniasis in the second or third trimesters ADRs Commonly Anorexia, nausea, abd pain, dizziness, HA; take with food to avoid GI irritation; Interactio ns CYP450 inhibitor cimetidine and inducers (phenytoin, phenobarbital); warfarin —monitor (PT/INR); disulfiram-like reaction with alcohol (avoid alcohol 48 hours after completion); elevate lithium level Clinical Use & dosing Metronidazole and tinidazole are used against the protozoal infections T. vaginalis, G. lamblia, and E. histolytica. Metronidazole is used for anaerobic bacterial infections, bacterial vaginosis, and is one of the drugs in H. pylori treatment. Monitorin g For giardiasis, if Sx persist, three stool samples & Cx sent several days apart 3-4wk after completion Education Take with food or snack for GI upset, sugarless candy for dry mouth and metallic taste; metronidazole cause harmless darkening of urine; superinfection (vaginal candidiasis); CNS Sx (ataxia, mood and mental changes, clumsiness, ataxia, seizures), peripheral neuropathy (numbness, tingling, pain, or weakness in hands or feet), and leukopenia (sore throat or fever)
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  • Spring '14
  • Henrikson,J
  • Clostridium difficile, Renal function

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