36 of the typical variation in the population for the

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36% of the typical variation in the population for the NPD trait is attributable to genetic variation B. 64% of the typical variation in the population for the NPD trait is due to environmental causes C. 60% of the typical variation in the population for the NPD trait is attributable to genetic variation D. 40% of the typical variation in the population for the NPD trait is attributable to genetic variation E. None of the above 20 At the DNA level, sickle cell anemia is caused by... A. A single nucleotide substitution that creates a nonsense mutation B. A single nucleotide substitution that creates a missense mutation C. A frameshift mutation D. A deletion of part or all of the gene E. a mutation in the promoter or enhancer
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Page 5 21 Which of the following does NOT occur during mitosis? A. Pairing and synapsis of homologous chromosomes B. Disjunction of sister chromatids C. chromosome condensation D. None of the above (A-C) happen during mitosis E. All of the above (A-C) happen during mitosis 22&23 THIS PROBLEM IS WORTH 2 POINTS – FILL IN BOTH NUMBERS ON YOUR SCANTRON Next 3 questions – A set of Hfr strains transfer markers in the following order: Strain Transfer order 1 A C D E 2 E D C A T 3 C A T F V B K 4 C D E Q K B Which of the following gene orders is correct? A: A T F V B K Q E D C B: A C D E T A C V B K Q C: A C D E T F V B K Q D: E D C A T F V K B Q E: C D E Q K B V F A T 24&25 THIS PROBLEM IS WORTH 2 POINTS – FILL IN BOTH NUMBERS ON YOUR SCANTRON Which Hfr strains have F factors inserted in the same orientation? A: 1 and 3 oriented the same way, 2 and 4 both oriented the other way B: 1 and 2 oriented the same way, 3 and 4 both oriented the other way C: 1 and 4 oriented the same way, 2 and 3 both oriented the other way D: 1 oriented one way, 2, 3 and 4 all oriented the other way E: all are oriented the same way 26&27 THIS PROBLEM IS WORTH 2 POINTS – FILL IN BOTH NUMBERS ON YOUR SCANTRON Imagine that you have at your disposal the set of strains listed above, that you perform a single conjugation experiment, and that you observe the following transfer order: C E D A Q K T. Which problem or mistake in the setup of the experiment could explain this result? A: Two donor Hfr strains were mixed with an F-­ recipient: strains 2 and 4 B: The F factor of the donor strain reverted to plasmid form C: The recipient was F+ instead of F-­ D: The growth medium did not counter-­select against donor cells E: The F factor inserted in the chromosome of strain 4 changed its insertion position 28&29 THIS PROBLEM IS WORTH 2 POINTS – FILL IN BOTH NUMBERS ON YOUR SCANTRON Which of the following would you NOT expect to be commonly found in a cloning vector? A: A gene that make cells resistant to the antibiotic ampicillin B: An origin of replication C: A phage gene that makes cells resistant to DNA damage D: A set of restriction enzymes recognition sites
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Page 6 30&31 THIS PROBLEM IS WORTH 2 POINTS – FILL IN BOTH NUMBERS ON YOUR SCANTRON Bob meets Leah in his summer school Bio93 class. Bob is a hard worker (homozygous for the H allele). Leah is lazy (homozygous for the h allele). The H locus is linked to a chromosomal
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