This unique feature needs further elaboration

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This unique feature needs further elaboration Weakness and Babinski positive  Due to corticospinal tract involvement. Abolition of tendon reflexes  Due to dorsal root ganglia involvement and peripheral nerve involvement. 170
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Associated features of Friedrich’s Ataxia:- Cardiomyopathy (90%) Diabetes (20%) Kyphoscoliosis Pescavus Optic atrophy Dementia 171
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Absent ankle jerk and extensor plantar response is found in - (PGI June 98) a) Friedreich’s ataxia b) Tabes dorsalis c) SACD d) Vit B deficiency A 172
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65 year old man presents with anaemia and posterior column dysfunction, the likely cause is - (May 95) a) B 1 deficit b)B 12- deficit c) SSPE d) Multiple selerosis 173
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SACD Patient with anaemia and postcolumn dysfunction is most likely suffering from subacute combined degeneration of the cord. (SACD). “SACD occurs due to vitamin B 12 deficiency.” Vitamin B 12 deficiency leads to megaloblastic anaemia and defects in myelination. 174
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Demyelination occurs predominantly in - Posterior column and • Pyramidaltract and later in the course Peripheral nerves are also involved 175
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Optic nerve atrophy - Sometimes visual impairment due to optic nerve atrophy may occassionally be the earliest or sole manifestation Mental symptoms:- Irritability, apathy, somnolene, suspiciousness, emotional unstability. 176
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65 year old man presents with anaemia and posterior column dysfunction, the likely cause is - (May 95) a) B 1 deficit b)B 12- deficit c) SSPE d) Multiple selerosis B 12 177
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Subacute combined degeneration due to Vit B 12 deficiency mainly involves – (PGI-DEC 03) a) Peripheral nerve b) Corticospinal tract c) Posterior column d) Spinocerebellar tract e) Spinothalamic tract 178
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The spinal cord, brain, optic nerves, peripheral nerves may all be affected in vitamin B12 deficiency but the spinal cord is usually affected first and exclusively. The tracts mainly involved in the spinal cord are: Posterior column. Corticospinal tract. Later on peripheral nerves are involved. 179
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Subacute combined degeneration due to to Vit B 12 deficiency mainly involves – (PGI-DEC 03) a) Peripheral nerve b) Corticospinal tract c) Posterior column d) Spinocerebellar tract e) Spinothalamic tract C , B , A 181
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Pyramidal tract involvement with absent ankle jerk is seen in - (AIIMSMay 2001) a) Frederich’s ataxia b) Subacute combined degeneration of the spinal cord c) Lathyrism d) Tabes dorsalis 182
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183
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Which of the following is not true about tabes Dorsalis- a) Seen in Neurosyphillis (NBE/DNB Pattern) b) Deep tendon reflexes are brisk c) Loss of vibration sense d) Acute abdominal pain and visceral symptoms 184
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Pathology: There is involvement of: Involvement of posterior root of lumbosacral region.
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  • Winter '16
  • jean grey

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