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3.
Mutations in DNA can have profound effects on the function of a protein. For each of the following
proteins – how have the amino acids chemical properties changed from each of the mutations? Then
explain how did these structural changes alter the amino acid interactions of the protein and affect its
function. TIE BREAKER
1 pt - a change from lysine (positive charge) at position 251 to lack of production of an
amino acid
4. Below is structural formula for tryptophan. Identify each compounds role and explain the biosynthesis
pathway of tryptophan  5-Hydroxtryptophan  Serotonin based on your knowledge of enzymes,
cofactors, and structural formulas. Be sure to include how each molecule changes structurally after each
reaction. (4 points) TIEBREAKER
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