But do they warrant separate chapters in a book on interac tions in crystals

But do they warrant separate chapters in a book on

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But do they warrant separate chapters in a book on interac- tions in crystals and Crystal Engineering? Halogen bonds are another story. These bonds are being actively researched today, and also in the Crystal Engineering context. I would have liked to see a little more coverage of this important topic in this book, including perhaps chalcogen and tetrel bonds. The final chapter by Braga and Grepioni brings the reader to the practice of Crystal Engineering itself and is well placed in a volume that occurs in an RSC series entitled ‘Funda- mentals of Crystal Engineering’. Many experimentalists who work in Crystal Engineering are thinking about polymorphs, hydrates and co-crystals. They want to know the properties of important intermolecular interactions that would help them to design crystals with better solubility and permeability prop- erties, if they work, say, with pharmaceuticals. Such researchers and students would constitute the main readership of a book such as this. These readers are not exactly worried about whether Crystal Engineering is ‘an area restricted to particular cases’ which might ‘succeed with educated guessing and a dash of luck’, or whether crystal structure prediction is the only real research frontier of tomorrow because it alone deals with the ‘extensive, quantitative evaluation of the implied energies’. The study of intermolecular interactions in crystals is now in the chemistry mainstream, and this book succeeds in capturing neither its importance nor its excite- ment. book reviews 254 Gautam R. Desiraju ± Book review Acta Cryst. (2018). B 74 , 253–254
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