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NE 101 Exam 3 Review Sheet '12

Computational neuro a we heard about a philosophy of

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VIII. Computational Neuro a. We heard about a philosophy of computational neuroscience that involves a three-pronged approach: i. Data ii. Analysis iii. Models b. Computational neuroscience is interdisciplinary. c. The brain is not exactly a computer. d. A network consists of two basic elements i. Nodes ii. Edges e. Networks are an important tool to understand the brain i. Structural networks represent anatomical connections ii. Functional networks represent similar activity between brain areas f. Brain connectivity perhaps has properties of a small-world network i. A small world network has short path length between nodes ii. A small world network has large clustering between nodes iii. Social networks are often small world networks g. The brain exhibits rhythms h. These are associated with disease and healthy function i. Data analysis is vital because we're overwhelmed with data j. One goal of modeling is to use mathematical equations to mimic an observed system i. Models can be simple or extremely difficult k. It's not known why seizures stop l. A critical transition or "tipping point" is a sudden shift in a system from one state to another m. We propose a mathematical model that seizures stop via a critical transition i. Status epilepticus is when a seizure fails to stop 3
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