Bacterial infections proliferation among fishes can, therefore, get acquired unintentionally by a human being through ingestion (Mukherjee et al., 2016). The Indians occasionally experience emerging outbreaks of bacterial infections, for example, salmonellosis and typhoid. Hence, resulting in individuals becoming victims of nosocomial diseases contracted from medical equipment and health facilities. Other consequences of the disorders may include a prolonged usage of antibiotics, increased hospital bills, as well as economic losses. According to Mukherjeeet al. (2016), drug resistance pervasiveness is currently a threat to the efficacy of the antibiotics used in the treatment of infections. Increased antibiotics dosage functions faster on pathogenic
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viruses, thus, leasing to an increased risk for neurotoxicity, hepatoxicity plus, several adverse effects to humans. As a way out, the development and discovery of new-fangled alternatives for available antibiotics are presently commercially promoted worldwide. New options of drugs from compounds extracted from animals, plants, and micro-organisms get considered as promising products. Substances produced naturally by organisms are relatively reasonable, cost-efficient, and environmentally friendly and have less serious side effects as compared to the commercially present antibiotics (Dash, Samal, and Thatoi, 2014). As a result, natural products antibacterial activities of organisms, particularly of wide-range of fish species has drawn interests as a promising source of compounds of antibiotics against fish and humans pathogens.India currently is the second-largest fish producer worldwide consisting of 6.3 percent of the total world fish production. It is a vital production mainly in its coastal states, making employment to over 14 million individuals. For example, during the 2017and 2018 season, the total output of fish got projected to be over 12.61 million metric tons and, inland fishing constituting 65 percent. On the other hand, culture fisheries represented about 50 percent of the total production (Jayanthi et al., 2018). Therefore, there might be a potency of antibiotic properties in the diverse fish species produced in India aquatic ecosystem.The primary goal of this research was to contribute to the general awareness of the search for novel antimicrobials. Therefore, this research explored extensively on an assessment of the potency of three major Indian fish of indigenous origin. The study examined the dominant skin mucus of Carp species, including Catla catla, Labeo rohita, andCirrinus mrigalaas an effective antimicrobial against human and fish pathogenic bacteria. The study particularly sought to test the effects of antimicrobial of the mucous against human and fish pathogenic bacteria to expoundon possible agents in the mucus of fish for drug discovery.
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