Sept 27 - Animals Lecture #6

Thc exogenous cannabinoid active substance from

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THC (exogenous cannabinoid) – active substance from cannabis sativa o Acts on central nervous system receptors Pharmacological actions – numerous, including hyperphagia Anandamide – endogenous cannaboid synthesized within nervous system o THC mimics anadamide by binding to the same receptors o Present in Hydra o Anandamide stimulates appetite in mammals (same thing as THC) Questioned whether anadamide would give a feeding response to hydra Hydra were exposed to glutathione to induce mouth opening response Get chart o Mouth closes faster with more anandamide
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Tuesday, September 27, 2011 Animal Lecture # 6 o Anandamide accelerated Hydra mouth closure (i.e. reduced time between mouth opening and closing) o Results demonstrate that the development of a nerve net in Hydra is important in the control of feeding activity o By making them close their mouth without food, they are stimulating hunger in the Hydras Mouth opens into gastrovascular cavity which communicates with cavities in the tentacles Digestion Gastrodermal gland cells secrete enzymes into gastrovascular cavity Digestion starts in the gastrovascular cavity Sensory Structures Medusae are mobile, therefore require sensory structures Ocelli - simple light receptors (phototaxis) Statocysts - for control of balance (gravity)
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  • Fall '08
  • Cnidaria, gastrovascular cavity, Animal Lecture

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