8 Calculate the probability of each genotype in a child for a mating of two

8 calculate the probability of each genotype in a

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8. Calculate the probability of each genotype in a child for a mating of two heterozygotes Aa x Aa (you may want to draw a Punnett square to help you). 25% 9. What are all possible blood types of children if their mother has type A and their father has type B blood? 10. From the situation in previous question, what genotypes the parents and children may have? 11. Explain how sex is determined in humans Sex is determined by the Y chromosome. The Y chromosome contains male genes. SRY gene forms the gonads into testis, and if its missing they turn into ovaries. 12. What is a sex-linked gene? A gene located on either sex chromosome. In humans, sex- linked usually refers to a gene on the X-chromosome, which is larger and contains more genes. 13. Give examples of sex-linked traits (diseases). Red-green color-blindness, and hemophilia 14. What is aneuploidy? Missing, or extra chromosomes. 15. What causes the Down’s syndrome? About 95 percent of the time, Down syndrome is caused by trisomy 21 — the person has three copies of chromosome 21, instead of the usual two copies, in all cells. This is caused by abnormal cell division during the development of the sperm cell or the egg cell. 16. Describe the following genetic conditions and indicate the type of inheritance pattern for each one: sickle-cell anemia albinism- inability to produce melanin, very white skin and hair, light/pink eyes. Increased sensitivity to sunburn and as a result skin cancer. Otherwise the person is normal. Best management is to avoid sunlight. Huntington’s disease- very severe lethal neurodegenerative disease, characterized by neurological and psychiatric symptoms. Starts very late, 30s and 40s, by which
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time many people have already reproduced (and possibly passed on the disease allele!) cystic fibrosis- very thick sticky mucus in various organs. Very serious disease,
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  • Fall '16
  • Lambrini Nicopoulos
  • Genetics, neurodegenerative disease

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