A meso compound a compound with two asymmetric

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A Meso Compound A compound with two asymmetric centers that have the same four groups bonded to each asymmetric center will have three stereoisomers: a meso compound and a pair of enantiomers.
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Naming Stereoisomers
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Naming Stereoisomers
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Physical Properties of Stereoisomers
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Stereochemistry Presents Challenges to Synthetic Chemistry In the 90s, over 30 teams worked to achieve a total synthesis Annual sales peaked in 2000, reaching US$ 1.6 billion; Paclitaxel is now available in generic form. A B C D
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Naltrexone – an opioid antagonist: binds opioid receptor with higher affinity than the agonist without activating the receptor Morphine – an opioid agonist: binds opioid receptor with activation Bupropion “Wellbutrin” Antidepressant/smoking cessation Contrave – weight-loss formulation FDA approved 9/10/14
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Controlling Stereochemistry is Critical in Drug Manufacture. Top 5 Drugs in 2013
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